cag, a pathogenicity island of Helicobacter pylori, encodes type I-specific and disease-associated virulence factors

cagA, a gene that codes for an immunodominant antigen, is present only in Helicobacter pylori strains that are associated with severe forms of gastroduodenal disease (type I strains). We found that the genetic locus that contains cagA (cag) is part of a 40-kb DNA insertion that likely was acquired h...

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Main Authors: Censini, Stefano, Lange, Christina, Xiang, Zhaoying, Crabtree, Jean E., Ghiara, Paolo, Borodovsky, Mark, Rappuoli, Rino, Covacci, Antonello
格式: Artigo
語言:Inglês
出版: The National Academy of Sciences of the USA 1996
主題:
Biological Sciences
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC26189/
https://ncbi.nlm.nih.gov/pubmed/8962108
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