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Biochemical Characterization of DNA Damage Checkpoint Complexes: Clamp Loader and Clamp Complexes with Specificity for 5′ Recessed DNA

The cellular pathways involved in maintaining genome stability halt cell cycle progression in the presence of DNA damage or incomplete replication. Proteins required for this pathway include Rad17, Rad9, Hus1, Rad1, and Rfc-2, Rfc-3, Rfc-4, and Rfc-5. The heteropentamer replication factor C (RFC) lo...

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Detalhes bibliográficos
Main Authors: Ellison, Viola, Stillman, Bruce
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC261875/
https://ncbi.nlm.nih.gov/pubmed/14624239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0000033
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