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Circulating Free Fatty Acids Are Increased Independent of PPARγ Activity Following Administration of Poloxamer 407 To Mice
Poloxamer 407 (P-407) is a copolymer surfactant that induces a dose-controlled dyslipidemia in both mice and rats. Human macrophages cultured with P-407 exhibit a concentration-dependent reduction in cholesterol efflux to apolipoprotein A1 (apoA1) linked to down-regulation of the ATP-binding cassett...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615679/ https://ncbi.nlm.nih.gov/pubmed/18758514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/y08-070 |
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