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Analysis of re-replication from deregulated origin licensing by DNA fiber spreading
A major challenge each human cell-division cycle is to ensure that DNA replication origins do not initiate more than once, a phenomenon known as re-replication. Acute deregulation of replication control ultimately causes extensive DNA damage, cell-cycle checkpoint activation and cell death whereas m...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615611/ https://ncbi.nlm.nih.gov/pubmed/19010964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn912 |
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