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Determinants of Cyclophilin A-dependent TRIM5α restriction against HIV-1
TRIM5α is a host protein that can bind to incoming retroviral capsid (CA) and inhibit retroviruses in a species-specific manner. The CA protein of HIV-1 also interacts with high affinity to the host protein cyclophilin A (CypA). This binding has been shown to positively affect some early stage of th...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615586/ https://ncbi.nlm.nih.gov/pubmed/18678385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.06.037 |
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