Oral vaccination of monkeys with an invasive Escherichia coli K-12 hybrid expressing Shigella flexneri 2a somatic antigen.

A living oral vaccine, designed to protect against Shigella flexneri 2a infections, was constructed by using Escherichia coli K-12 as a carrier strain. The hybrid strain, designated EC104, contained both chromosomal and plasmid genes from S. flexneri donor strains. In addition to expressing the S. f...

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Detalhes bibliográficos
Main Authors: Formal, S B, Hale, T L, Kapfer, C, Cogan, J P, Snoy, P J, Chung, R, Wingfield, M E, Elisberg, B L, Baron, L S
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC261556/
https://ncbi.nlm.nih.gov/pubmed/6389344
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