Safety, immunogenicity, and efficacy in monkeys and humans of invasive Escherichia coli K-12 hybrid vaccine candidates expressing Shigella flexneri 2a somatic antigen.

A live, oral Shigella vaccine, constructed by transfer of the 140-MDa invasiveness plasmid from Shigella flexneri 5 and the chromosomal genes encoding the group- and type-specific O antigen of S. flexneri 2a to Escherichia coli K-12, was tested in humans. Designated EcSf2a-1, this vaccine produced a...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kotloff, K L, Herrington, D A, Hale, T L, Newland, J W, Van De Verg, L, Cogan, J P, Snoy, P J, Sadoff, J C, Formal, S B, Levine, M M
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC257146/
https://ncbi.nlm.nih.gov/pubmed/1587589
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados