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Regulation of growth and survival of activated T cells by cell-transducing inhibitors of Ras

We describe the development of cell-penetrating inhibitors of Ras and study their ability to inhibit T cell activation. The inhibitors transduced T cells in a time and concentration-dependent manner and interacted with endogenous Ras. Anti-CD3/CD28-activated cells when treated with the inhibitors, e...

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Bibliografiske detaljer
Main Authors: Malik, Nasser M., Gilroy, Derek W., Kabouridis, Panagiotis S.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science B.V 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615550/
https://ncbi.nlm.nih.gov/pubmed/19063885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.11.042
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