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Regulation of growth and survival of activated T cells by cell-transducing inhibitors of Ras
We describe the development of cell-penetrating inhibitors of Ras and study their ability to inhibit T cell activation. The inhibitors transduced T cells in a time and concentration-dependent manner and interacted with endogenous Ras. Anti-CD3/CD28-activated cells when treated with the inhibitors, e...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier Science B.V
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615550/ https://ncbi.nlm.nih.gov/pubmed/19063885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2008.11.042 |
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