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Direct Interaction of Otoferlin with Syntaxin 1A, SNAP-25, and the L-type Voltage-gated Calcium Channel Ca(V)1.3
The molecular mechanisms underlying synaptic exocytosis in the hair cell, the auditory and vestibular receptor cell, are not well understood. Otoferlin, a C2 domain-containing Ca(2+)-binding protein, has been implicated as having a role in vesicular release. Mutations in the OTOF gene cause nonsyndr...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2009
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615516/ https://ncbi.nlm.nih.gov/pubmed/19004828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803605200 |
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