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Direct Interaction of Otoferlin with Syntaxin 1A, SNAP-25, and the L-type Voltage-gated Calcium Channel Ca(V)1.3

The molecular mechanisms underlying synaptic exocytosis in the hair cell, the auditory and vestibular receptor cell, are not well understood. Otoferlin, a C2 domain-containing Ca(2+)-binding protein, has been implicated as having a role in vesicular release. Mutations in the OTOF gene cause nonsyndr...

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Autors principals: Ramakrishnan, Neeliyath A., Drescher, Marian J., Drescher, Dennis G.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615516/
https://ncbi.nlm.nih.gov/pubmed/19004828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803605200
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