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Structure of yeast poly(A) polymerase in complex with a peptide from Fip1, an intrinsically-disordered protein

In yeast, the mRNA processing enzyme, poly(A) polymerase is tethered to the much larger 3′-end processing complex via Fip1, a 36 kDa protein of unknown structure. We report the 2.6 Angstrom crystal structure of yeast poly(A) polymerase in complex with a peptide containing residues 80–105 of Fip1. Th...

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Bibliografiska uppgifter
Huvudupphovsmän: Meinke, Gretchen, Ezeokonkwo, Chukwudi, Balbo, Paul, Stafford, Walter, Moore, Claire, Bohm, Andrew
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615413/
https://ncbi.nlm.nih.gov/pubmed/18537269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800204k
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