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Mutations in the middle domain of yeast poly(A) polymerase affect interactions with RNA but not ATP

The eukaryotic poly(A) polymerase (PAP) is responsible for the posttranscriptional extension of mRNA 3′ ends by the addition of a poly(A) tract. The recently published three-dimensional structures of yeast and bovine PAPs have made a more directed biochemical analysis of this enzyme possible. Based...

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Hlavní autoři: ZHELKOVSKY, ALEXANDER, HELMLING, STEFFEN, BOHM, ANDREW, MOORE, CLAIRE
Médium: Artigo
Jazyk:Inglês
Vydáno: Copyright 2004 by RNA Society 2004
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1370545/
https://ncbi.nlm.nih.gov/pubmed/15037764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.5238704
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