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The Target of Rapamycin (TOR) pathway antagonizes pha-4/FoxA to control development and aging

BACKGROUND: FoxA factors are critical regulators of embryonic development and post-embryonic life, but little is know about the upstream pathways that modulate their activity [1]. C. elegans pha-4 encodes a FoxA transcription factor that is required to establish the foregut in embryos, and to contro...

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Main Authors: Sheaffer, Karyn L., Updike, Dustin L., Mango, Susan E.
格式: Artigo
語言:Inglês
出版: 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615410/
https://ncbi.nlm.nih.gov/pubmed/18804378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.07.097
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