P2Y6 Receptors Require an Intact Cysteinyl Leukotriene Synthetic and Signaling System to Induce Survival and Activation of Mast Cells(1)

Cysteinyl leukotrienes (cys-LTs) induce inflammatory responses through type 1 (CysLT(1)R) and type 2 (CysLT(2)R) cys-LT receptors, and activate mast cells (MCs) in vitro. We previously demonstrated that cys-LTs cross-desensitized interleukin (IL)-4-primed primary human MCs (hMCs) to stimulation with...

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Hlavní autoři: Jiang, Yongfeng, Borrelli, Laura, Bacskai, Brian J., Kanaoka, Yoshihide, Boyce, Joshua A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615395/
https://ncbi.nlm.nih.gov/pubmed/19124756
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