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Metabolomic and flux-balance analysis of age-related decline of hypoxia tolerance in Drosophila muscle tissue

The fruitfly Drosophila melanogaster is increasingly used as a model organism for studying acute hypoxia tolerance and for studying aging, but the interactions between these two factors are not well known. Here we show that hypoxia tolerance degrades with age in post-hypoxic recovery of whole-body m...

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Autori principali: Coquin, Laurence, Feala, Jacob D, McCulloch, Andrew D, Paternostro, Giovanni
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615305/
https://ncbi.nlm.nih.gov/pubmed/19096360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2008.71
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