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Flexibility in energy metabolism supports hypoxia tolerance in Drosophila flight muscle: metabolomic and computational systems analysis

The fruitfly Drosophila melanogaster offers promise as a genetically tractable model for studying adaptation to hypoxia at the cellular level, but the metabolic basis for extreme hypoxia tolerance in flies is not well known. Using (1)H NMR spectroscopy, metabolomic profiles were collected under hypo...

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Detalhes bibliográficos
Main Authors: Feala, Jacob D, Coquin, Laurence, McCulloch, Andrew D, Paternostro, Giovanni
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1865581/
https://ncbi.nlm.nih.gov/pubmed/17437024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb4100139
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