Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice

Ceramide transfer protein (CERT) functions in the transfer of ceramide from the endoplasmic reticulum (ER) to the Golgi. In this study, we show that CERT is an essential gene for mouse development and embryonic survival and, quite strikingly, is critical for mitochondrial integrity. CERT mutant embr...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Wang, Xin, Rao, Raghavendra Pralhada, Kosakowska-Cholody, Teresa, Masood, M. Athar, Southon, Eileen, Zhang, Helin, Berthet, Cyril, Nagashim, Kunio, Veenstra, Timothy K., Tessarollo, Lino, Acharya, Usha, Acharya, Jairaj K.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2009
Aiheet:
Research Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615084/
https://ncbi.nlm.nih.gov/pubmed/19139267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200807176
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia