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Functional and Structural Roles of the Cys14-Cys38 Disulfide of Bovine Pancreatic Trypsin Inhibitor

The disulfide bond between Cys14 and Cys38 of bovine pancreatic trypsin inhibitor (BPTI) lies on the surface of the inhibitor and forms part of the protease binding region. The functional properties of three variants lacking this disulfide, with one or both of the Cys residues replaced with Ser, wer...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Zakharova, Elena, Horvath, Martin P., Goldenberg, David P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615049/
https://ncbi.nlm.nih.gov/pubmed/18692070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.07.063
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