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Heterozygosity increases microsatellite mutation rate, linking it to demographic history
BACKGROUND: Biochemical experiments in yeast suggest a possible mechanism that would cause heterozygous sites to mutate faster than equivalent homozygous sites. If such a process operates, it could undermine a key assumption at the core of population genetic theory, namely that mutation rate and pop...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2008
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2615044/ https://ncbi.nlm.nih.gov/pubmed/19014581 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-9-72 |
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