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Heterozygosity increases microsatellite mutation rate, linking it to demographic history

BACKGROUND: Biochemical experiments in yeast suggest a possible mechanism that would cause heterozygous sites to mutate faster than equivalent homozygous sites. If such a process operates, it could undermine a key assumption at the core of population genetic theory, namely that mutation rate and pop...

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Detalhes bibliográficos
Main Authors: Amos, William, Flint, Jonathan, Xu, Xin
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2615044/
https://ncbi.nlm.nih.gov/pubmed/19014581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2156-9-72
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