MECP2 PROMOTER METHYLATION AND X CHROMOSOME INACTIVATION IN AUTISM

Epigenetic mechanisms have been proposed to play a role in the etiology of autism. This hypothesis is supported by the discovery of increased MECP2 promoter methylation associated with decreased MeCP2 protein expression in autism male brain. To further understand the influence of female X chromosome...

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Autori principali: Nagarajan, Raman P., Patzel, Katherine A., Martin, Michelle, Yasui, Dag H., Swanberg, Susan E., Hertz-Picciotto, Irva, Hansen, Robin L., Van de Water, Judy, Pessah, Isaac N., Jiang, Ruby, Robinson, Wendy P., LaSalle, Janine M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614877/
https://ncbi.nlm.nih.gov/pubmed/19132145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/aur.24
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