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15q11-13 GABA(A) receptor genes are normally biallelically expressed in brain yet are subject to epigenetic dysregulation in autism-spectrum disorders

Human chromosome 15q11-13 is a complex locus containing imprinted genes as well as a cluster of three GABA(A) receptor subunit (GABR) genes, GABRB3, GABRA5, and GABRG3. Deletion or duplication of 15q11-13 GABR genes occurs in multiple human neurodevelopmental disorders including Prader-Willi syndrom...

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Autors principals: Hogart, Amber, Nagarajan, Raman P., Patzel, Katherine A., Yasui, Dag H., LaSalle, Janine M.
Format: Artigo
Idioma:Inglês
Publicat: 2007
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1934608/
https://ncbi.nlm.nih.gov/pubmed/17339270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddm014
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