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Chronic Restraint Stress Promotes Immune Suppression through Toll-like Receptor 4-Mediated Phosphoinositide 3-kinase Signaling

Stress, either psychological or physical, can have a dramatic impact on the immune system. Toll-like receptors (TLRs) play a pivotal role in the induction of innate and adaptive immune response. We have reported that stress modulates the immune response in a TLR4-dependent manner. However, the mecha...

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Hlavní autoři: Zhang, Yi, Zhang, Ying, Miao, Junying, Hanley, Gregory, Stuart, Charles, Sun, Xiuli, Chen, Tingting, Yin, Deling
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614832/
https://ncbi.nlm.nih.gov/pubmed/18814920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2008.08.011
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