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Calpain 3, the “gatekeeper” of proper sarcomere assembly, turnover and maintenance

Calpain 3 is a member of the calpain family of calcium-dependent intracellular proteases. Thirteen years ago it was discovered that mutations in calpain 3 (CAPN3) result in an autosomal recessive and progressive form of limb girdle muscular dystrophy called limb girdle muscular dystrophy type 2A. Wh...

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Détails bibliographiques
Auteurs principaux: Beckmann, Jacques S, Spencer, Melissa
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614824/
https://ncbi.nlm.nih.gov/pubmed/18974005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nmd.2008.08.005
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