Targeted inactivation of MLL3 histone H3–Lys-4 methyltransferase activity in the mouse reveals vital roles for MLL3 in adipogenesis

Activating signal cointegrator-2 (ASC-2), a transcriptional coactivator of multiple transcription factors that include the adipogenic factors peroxisome proliferator-activated receptor γ (PPARγ) and C/EBPα, is associated with histone H3-Lys-4-methyltransferase (H3K4MT) MLL3 or its paralogue MLL4 in...

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Autors principals: Lee, Jeongkyung, Saha, Pradip K., Yang, Qi-Heng, Lee, Seunghee, Park, Jung Yoon, Suh, Yousin, Lee, Soo-Kyung, Chan, Lawrence, Roeder, Robert G., Lee, Jae W.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2008
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614744/
https://ncbi.nlm.nih.gov/pubmed/19047629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810100105
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