Conversion of DNA gyrase into a conventional type II topoisomerase
DNA gyrase is unique among topoisomerases in its ability to introduce negative supercoils into closed-circular DNA. We have demonstrated that deletion of the C-terminal DNA-binding domain of the A subunit of gyrase gives rise to an enzyme that cannot supercoil DNA but relaxes DNA in an ATP-dependent...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Principais autores: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1996
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26147/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8962066/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.25.14416 |
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