Umbilical Cord Blood T cells Express Multiple Natural Cytotoxicity Receptors After IL-15 Stimulation, but Only NKp30 Is Functional

The natural cytotoxicity receptors (NCRs), NKp30, NKp44 and NKp46, are thought to be NK lineage restricted. Here we show that IL-15 induces NCR expression on umbilical cord blood (UCB) T cells. NCRs were mainly on CD8(+) and CD56(+) UCB T cells. Only NKp30 was functional as demonstrated by degranula...

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Bibliografiske detaljer
Main Authors: Tang, Qin, Grzywacz, Bartosz, Wang, Hongbo, Kataria, Nandini, Cao, Qing, Wagner, John E., Blazar, Bruce R., Miller, Jeffrey S., Verneris, Michael R.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614673/
https://ncbi.nlm.nih.gov/pubmed/18802053
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