Role of TNF-α-induced reactive oxygen species in endothelial dysfunction during reperfusion injury

We hypothesized that neutralization of TNF-α at the time of reperfusion exerts a salubrious role on endothelial function and reduces the production of reactive oxygen species. We employed a mouse model of myocardial ischemia-reperfusion (I/R, 30 min/90 min) and administered TNF-α neutralizing antibo...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Gao , Xue, Zhang, Hanrui, Belmadani, Souad, Wu, Junxi, Xu, Xiangbin, Elford, Howard, Potter, Barry J., Zhang, Cuihua
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2008
Sujets:
Translational Physiology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614540/
https://ncbi.nlm.nih.gov/pubmed/18849334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00587.2008
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