VEGF is critical for stem cell-mediated cardioprotection and a crucial paracrine factor for defining the age threshold in adult and neonatal stem cell function

Bone marrow mesenchymal stem cells (MSCs) may be a novel treatment modality for organ ischemia, possibly through the release of beneficial paracrine factors. However, an age threshold likely exists as to when MSCs gain their beneficial protective properties. We hypothesized that 1) VEGF would be a c...

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Detalhes bibliográficos
Main Authors: Markel, Troy A., Wang, Yue, Herrmann, Jeremy L., Crisostomo, Paul R., Wang, Meijing, Novotny, Nathan M., Herring, Christine M., Tan, Jiangning, Lahm, Tim, Meldrum, Daniel R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614539/
https://ncbi.nlm.nih.gov/pubmed/18849336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00565.2008
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