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HIV-infected macrophages mediate neuronal apoptosis through mitochondrial glutaminase

A significant number of patients infected with human immunodeficiency virus-1 (HIV-1) suffer cognitive impairment ranging from mild to severe HIV-associated dementia (HAD), a result of neuronal degeneration in the basal ganglia, cerebral cortex and hippocampus. Mononuclear phagocyte dysfunction is t...

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Detalhes bibliográficos
Main Authors: Tian, Changhai, Erdmann, Nathan, Zhao, Jianxing, Cao, Zhijun, Peng, Hui, Zheng, Jialin
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614440/
https://ncbi.nlm.nih.gov/pubmed/18088378
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2007.05197.x
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