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Lid2, a JmjC domain-Containing Histone Demethylase, is Required for Coordinating H3K4 and H3K9 Methylation of Heterochromatin and Euchromatin
In most eukaryotes, histone methylation patterns regulate chromatin architecture and function: methylation of histone H3 lysine-9 (H3K9) demarcates heterochromatin while H3K4 methylation demarcates euchromatin. We show here that the S. pombe JmjC-domain protein Lid2 is a trimethyl H3K4 demethylase r...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614271/ https://ncbi.nlm.nih.gov/pubmed/18957202 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.08.036 |
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