Lid2, a JmjC domain-Containing Histone Demethylase, is Required for Coordinating H3K4 and H3K9 Methylation of Heterochromatin and Euchromatin

In most eukaryotes, histone methylation patterns regulate chromatin architecture and function: methylation of histone H3 lysine-9 (H3K9) demarcates heterochromatin while H3K4 methylation demarcates euchromatin. We show here that the S. pombe JmjC-domain protein Lid2 is a trimethyl H3K4 demethylase r...

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Huvudupphovsmän: Li, Fei, Huarte, Maite, Zaratiegui, Mikel, Vaughn, Matthew W., Shi, Yang, Martienssen, Rob, Cande, W. Zacheus
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2008
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614271/
https://ncbi.nlm.nih.gov/pubmed/18957202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2008.08.036
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