Mouse Genome-Wide Association Mapping Needs Linkage Analysis to Avoid False-Positive Loci

We carried out genome-wide association (GWA) studies in inbred mouse strains characterized for their lung tumor susceptibility phenotypes (spontaneous or urethane-induced) with panels of 12,959 (13K) or 138,793 (140K) single-nucleotide polymorphisms (SNPs). Above the statistical thresholds, we detec...

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Autores principales: Manenti, Giacomo, Galvan, Antonella, Pettinicchio, Angela, Trincucci, Gaia, Spada, Elena, Zolin, Anna, Milani, Silvano, Gonzalez-Neira, Anna, Dragani, Tommaso A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2009
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614123/
https://ncbi.nlm.nih.gov/pubmed/19132132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000331
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