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Temporally induced Nurr1 can induce a non-neuronal dopaminergic cell type in embryonic stem cell differentiation

The nuclear transcription factor Nurr1 is involved in the development and maintenance of the midbrain dopaminergic (DA) neuronal phenotype. We analysed the cellular and biological effects of Nurr1 during embryonic stem (ES) cell differentiation using the ROSA26-engineered Tet-inducible ES cell line...

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Main Authors: Sonntag, Kai-Christian, Simantov, Rabi, Kim, Kwang-Soo, Isacson, Ole
Formato: Artigo
Idioma:Inglês
Publicado: 2004
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2614072/
https://ncbi.nlm.nih.gov/pubmed/15016073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2004.03204.x
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