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A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic analysis

BACKGROUND: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) are the most effective and accurate methods for solving these problems. A key step to improve the performance of the SVM-...

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Detalhes bibliográficos
Main Authors: Liu, Bin, Wang, Xiaolong, Lin, Lei, Dong, Qiwen, Wang, Xuan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613933/
https://ncbi.nlm.nih.gov/pubmed/19046430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-510
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