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Application of nonnegative matrix factorization to improve profile-profile alignment features for fold recognition and remote homolog detection

BACKGROUND: Nonnegative matrix factorization (NMF) is a feature extraction method that has the property of intuitive part-based representation of the original features. This unique ability makes NMF a potentially promising method for biological sequence analysis. Here, we apply NMF to fold recogniti...

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Detalhes bibliográficos
Main Authors: Jung, Inkyung, Lee, Jaehyung, Lee, Soo-Young, Kim, Dongsup
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2459191/
https://ncbi.nlm.nih.gov/pubmed/18590572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-9-298
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