Intraflagellar Transport Protein 172 is essential for primary cilia formation and plays a vital role in patterning the mammalian brain

IFT172, also known as Selective Lim-domain Binding protein (SLB), is a component of the Intraflagellar Transport (IFT) complex. In order to evaluate the biological role of the Ift172 gene, we generated a loss-of-function mutation in the mouse. The resulting Slb mutant embryos die between E12.5–13.0,...

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Main Authors: Gorivodsky, Marat, Mukhopadhyay, Mahua, Wilsch-Braeuninger, Michaela, Phillips, Matthew, Teufel, Andreas, Kim, Changmee, Malik, Nasir, Huttner, Wieland, Westphal, Heiner
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613858/
https://ncbi.nlm.nih.gov/pubmed/18930042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.09.019
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