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Expression, activity and function of phosphodiesterases in the mature and immature ductus arteriosus

A patent ductus arteriosus is due in large part to increased sensitivity of the premature ductus to PGE2. Following PGE2 stimulation, cAMP concentrations are higher in the immature than in the mature ductus. cAMP concentrations depend on the rates of adenyl cyclase production and phosphodiesterase (...

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Detalhes bibliográficos
Main Authors: Liu, Hanguan, Manganiello, Vincent, Waleh, Nahid, Clyman, Ronald I.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613857/
https://ncbi.nlm.nih.gov/pubmed/18552705
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e3181827c2c
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