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A multicenter phase II trial of intrathecal topotecan in patients with meningeal malignancies
To determine the therapeutic efficacy (13-week and 26-week CNS progression-free survival [PFS], response rate, and overall survival) and safety of intraventricular (IVent) topotecan in patients with neoplastic meningitis (NM), we conducted a phase II, open-label, nonrandomized, single-arm trial of I...
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Main Authors: | , , , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Duke University Press
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613823/ https://ncbi.nlm.nih.gov/pubmed/18316473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2007-059 |
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