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53BP1 promotes NHEJ of telomeres by increasing chromatin mobility
Double strand breaks (DSBs) activate the ATM kinase which promotes the accumulation of DNA damage factors in the chromatin surrounding the break. The functional significance of the resulting DNA damage foci is poorly understood. Here we show that 53BP1, a component of DNA damage foci, changes the dy...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613650/ https://ncbi.nlm.nih.gov/pubmed/18931659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature07433 |
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