Control of TANK-binding Kinase 1-mediated Signaling by the γ(1)34.5 Protein of Herpes Simplex Virus 1

TANK-binding kinase 1 (TBK1) is a key component of Toll-like receptor-dependent and -independent signaling pathways. In response to microbial components, TBK1 activates interferon regulatory factor 3 (IRF3) and cytokine expression. Here we show that TBK1 is a novel target of the γ(1)34.5 protein, a...

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Hlavní autoři: Verpooten, Dustin, Ma, Yijie, Hou, Songwang, Yan, Zhipeng, He, Bin
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
Mechanisms of Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613634/
https://ncbi.nlm.nih.gov/pubmed/19010780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805905200
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