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Control of TANK-binding Kinase 1-mediated Signaling by the γ(1)34.5 Protein of Herpes Simplex Virus 1
TANK-binding kinase 1 (TBK1) is a key component of Toll-like receptor-dependent and -independent signaling pathways. In response to microbial components, TBK1 activates interferon regulatory factor 3 (IRF3) and cytokine expression. Here we show that TBK1 is a novel target of the γ(1)34.5 protein, a...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2613634/ https://ncbi.nlm.nih.gov/pubmed/19010780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805905200 |
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