MacB ABC Transporter Is a Dimer Whose ATPase Activity and Macrolide-binding Capacity Are Regulated by the Membrane Fusion Protein MacA

Gram-negative bacteria utilize specialized machinery to translocate drugs and protein toxins across the inner and outer membranes, consisting of a tripartite complex composed of an inner membrane secondary or primary active transporter (IMP), a periplasmic membrane fusion protein, and an outer membr...

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Autors principals: Lin, Hong Ting, Bavro, Vassiliy N., Barrera, Nelson P., Frankish, Helen M., Velamakanni, Saroj, van Veen, Hendrik W., Robinson, Carol V., Borges-Walmsley, M. Inês, Walmsley, Adrian R.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
Matèries:
Membrane Transport, Structure, Function, and Biogenesis
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613632/
https://ncbi.nlm.nih.gov/pubmed/18955484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806964200
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