Lipid-engineered Escherichia coli Membranes Reveal Critical Lipid Headgroup Size for Protein Function

Escherichia coli membranes have a substantial bilayer curvature stress due to a large fraction of the nonbilayer-prone lipid phosphatidylethanolamine, and a mutant (AD93) lacking this lipid is severely crippled in several membrane-associated processes. Introduction of four lipid glycosyltransferases...

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Bibliographic Details
Main Authors: Wikström, Malin, Kelly, Amélie A., Georgiev, Alexander, Eriksson, Hanna M., Klement, Maria Rosén, Bogdanov, Mikhail, Dowhan, William, Wieslander, Åke
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2009
Subjects:
Membrane Transport, Structure, Function, and Biogenesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613627/
https://ncbi.nlm.nih.gov/pubmed/18981182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804482200
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