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Sprouty 2 Regulates DNA Damage-induced Apoptosis in Ras-transformed Human Fibroblasts

We have reported that expression of Sprouty 2 (Spry2) is necessary for tumor formation by HRas(V12)-transformed fibroblasts. We now report on the role of Spry2 in the inhibition of UV(254 nm) radiation-induced apoptosis in HRas(V12)-transformed human fibroblasts. Silencing Spry2 in this context resu...

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Библиографические подробности
Главные авторы: Lito, Piro, Mets, Bryan D., Appledorn, Daniel M., Maher, Veronica M., McCormick, J. Justin
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2009
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613613/
https://ncbi.nlm.nih.gov/pubmed/19008219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808045200
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