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SPARC Inhibits Adipogenesis by Its Enhancement of β-Catenin Signaling

SPARC (secreted protein acidic and rich in cysteine) modulates interactions between cells and extracellular matrix and is enriched in white adipose tissue. We have reported that SPARC-null mice accumulate significantly more fat than wild-type mice and maintain relatively high levels of serum leptin....

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Autores principales: Nie, Jing, Sage, E. Helene
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613608/
https://ncbi.nlm.nih.gov/pubmed/18990699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808285200
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