The Copper Binding Domain of SPARC Mediates Cell Survival in Vitro via Interaction with Integrin β1 and Activation of Integrin-linked Kinase

Secreted protein acidic and rich in cysteine (SPARC) is important for the normal growth and maintenance of the murine lens. SPARC-null animals develop cataracts associated with a derangement of the lens capsule basement membrane and alterations in lens fiber morphology. Cellular stress and disregula...

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Bibliographische Detailangaben
Hauptverfasser: Weaver, Matt S., Workman, Gail, Sage, E. Helene
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Glycobiology and Extracellular Matrices
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2504874/
https://ncbi.nlm.nih.gov/pubmed/18503049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M706563200
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