Mitochondrial function and morphology are impaired in parkin mutant fibroblasts

OBJECTIVE: There are marked mitochondrial abnormalities in parkin-knock out drosophila and other model systems. The aim of our study was to determine mitochondrial function and morphology in parkin-mutant patients. We also investigated whether pharmacological rescue of impaired mitochondrial functio...

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Detalhes bibliográficos
Main Authors: Mortiboys, Heather, Thomas, Kelly Jean, Koopman, Werner J.H., Klaffke, Stefanie, Abou-Sleiman, Patrick, Olpin, Simon, Wood, Nicholas W, Willems, Peter H.G.M., Smeitink, Jan A.M., Cookson, Mark R, Bandmann, Oliver
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613566/
https://ncbi.nlm.nih.gov/pubmed/19067348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21492
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