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CD36 modulates migration of mouse and human macrophages in response to oxidized LDL and may contribute to macrophage trapping in the arterial intima

The trapping of lipid-laden macrophages in the arterial intima is a critical but reversible step in atherogenesis. However, the mechanism by which this occurs is not clearly defined. Here, we tested in mice the hypothesis that CD36, a class B scavenger receptor expressed on macrophages, has a role i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Park, Young Mi, Febbraio, Maria, Silverstein, Roy L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613464/
https://ncbi.nlm.nih.gov/pubmed/19065049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35535
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