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A specific CD36-dependent signaling pathway is required for platelet activation by oxLDL

Platelet hyperactivity associated with hyperlipidemia may contribute to development of a pro-thrombotic state. We previously showed that oxidized LDL (oxLDL) formed in the setting of hyperlipidemia and atherosclerosis activated platelets in a CD36 dependent manner. We now show that MAP kinase JNK2 a...

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Autori principali: Chen, Kan, Febbraio, Maria, Li, Wei, Silverstein, Roy L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749986/
https://ncbi.nlm.nih.gov/pubmed/18497330
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.172064
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