Enhanced production of nitric oxide, reactive oxygen species, and pro-inflammatory cytokines in very long chain saturated fatty acid-accumulated macrophages

BACKGROUND: Deterioration of peroxisomal β-oxidation activity causes an accumulation of very long chain saturated fatty acids (VLCSFA) in various organs. We have recently reported that the levels of VLCSFA in the plasma and/or membranes of blood cells were significantly higher in patients with metab...

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Main Authors: Yanagisawa, Naotake, Shimada, Kazunori, Miyazaki, Tetsuro, Kume, Atsumi, Kitamura, Yohei, Sumiyoshi, Katsuhiko, Kiyanagi, Takashi, Iesaki, Takafumi, Inoue, Nao, Daida, Hiroyuki
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2008
Teme:
Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613382/
https://ncbi.nlm.nih.gov/pubmed/19038055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-511X-7-48
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