Ribosome-induced changes in elongation factor Tu conformation control GTP hydrolysis

In translation, elongation factor Tu (EF-Tu) molecules deliver aminoacyl-tRNAs to the mRNA-programmed ribosome. The GTPase activity of EF-Tu is triggered by ribosome-induced conformational changes of the factor that play a pivotal role in the selection of the cognate aminoacyl-tRNAs. We present a 6....

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Detalhes bibliográficos
Main Authors: Villa, Elizabeth, Sengupta, Jayati, Trabuco, Leonardo G., LeBarron, Jamie, Baxter, William T., Shaikh, Tanvir R., Grassucci, Robert A., Nissen, Poul, Ehrenberg, Måns, Schulten, Klaus, Frank, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613361/
https://ncbi.nlm.nih.gov/pubmed/19122150
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811370106
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