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Oxidation of microbial iron-sulfur centers by the myeloperoxidase-H2O2-halide antimicrobial system.

Myeloperoxidase, H2O2, and a halide (chloride, bromide, or iodide) form a potent microbicidal system that contributes to the antimicrobial activity of neutrophils. The mechanism of toxicity is not completely understood. Powerful oxidants are formed that presumably attack the microbe at a variety of...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Infect Immun
Hauptverfasser: Rosen, H, Klebanoff, S J
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1985
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC261335/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2982737/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.47.3.613-618.1985
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